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Company ReportsDeciphera Pharmaceuticals

Deciphera Pharmaceuticals(DCPH)

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Qinlock	Ripretinib	2020-05-15	2030-2042	Gastrointestinal stromal tumors

Clinical Trials

Therapeutic Areas:

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Status:

All

Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

systemic mastocytosis

,

,

,

gastrointestinal diseases

,

digestive system diseases

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

neoplasms by histologic type

,

connective and soft tissue neoplasms

,

connective tissue neoplasms

,

gastrointestinal stromal tumors

,

,

,

,

malignant fibrous histiocytoma

,

graft vs host disease

,

bronchiolitis obliterans syndrome

,

,

,

giant cell tumors

,

pigmented villonodular synovitis

,

giant cell tumor of tendon sheath

breast neoplasms

,

triple negative breast neoplasms

,

,

cytomegalovirus retinitis

,

healthy volunteers/patients

,

renal cell carcinoma

,

,

muscular atrophy

,

spinal muscular atrophy

,

,

,

uterine cervical neoplasms

,

,

chronic hepatitis d

,

,

rheumatoid arthritis

,

,

,

,

,

chronic hepatitis c

,

chronic hepatitis

,

clear cell sarcoma

,

aids-related complex

,

diffuse intrinsic pontine glioma

,

,

myeloid sarcoma

,

primitive neuroectodermal tumors peripheral

,

atherosclerosis

,

,

basal cell carcinoma

,

basal cell neoplasms

,

synovial sarcoma

,

,

hidradenitis suppurativa

,

,

,

cytomegalovirus

,

,

muscular dystrophies

,

second primary neoplasms

,

,

hereditary breast and ovarian cancer syndrome

,

paraproteinemias

,

,

carcinoid tumor

,

respiratory syncytial virus infections

,

,

myasthenia gravis

,

muscle weakness

,

,

acinar cell carcinoma

,

conjunctival neoplasms

,

gastrointestinal stromal tumors

,

salivary gland neoplasms

,

breast diseases

,

medullary carcinoma

,

mammary paget's disease

,

parkinsonian disorders

,

pharmacokinetics

,

neoplasms by histologic type

,

optic nerve diseases

,

optic nerve injuries

,

lymphatic metastasis

,

blood platelet disorders

,

colorectal neoplasms

,

follicular lymphoma

,

mantle-cell lymphoma

,

,

,

germ cell and embryonal neoplasms

,

myelodysplastic-myeloproliferative diseases

,

fallopian tube neoplasms

,

healthy volunteers/patients

,

liver neoplasms

,

,

t-cell lymphoma

,

,

biphenotypic leukemia acute

,

,

t-cell lymphoma peripheral

,

squamous cell carcinoma of head and neck

,

eyelid neoplasms

,

b-cell lymphoma marginal zone

,

burkitt lymphoma

,

,

colonic neoplasms

,

,

bone marrow failure disorders

,

myeloid leukemia accelerated phase

,

plasma cell leukemia

,

castration-resistant prostatic neoplasms

,

malignant mesothelioma

,

,

uterine cervical neoplasms

,

peritoneal neoplasms

,

squamous cell carcinoma

,

fanconi syndrome

,

acquired immunodeficiency syndrome

,

alzheimer disease

,

parkinson disease

,

oligodendroglioma

,

esophageal neoplasms

,

hepatocellular carcinoma

,

myelomonocytic leukemia acute

,

waldenstrom macroglobulinemia

,

cardiomyopathies

,

acute lung injury

,

newborn respiratory distress syndrome

,

,

smoldering multiple myeloma

,

squamous cell neoplasms

,

prolymphocytic leukemia

,

large-cell lymphoma anaplastic

,

autologous transplantation

,

testicular neoplasms

,

cholangiocarcinoma

,

rectal neoplasms

,

,

neuroendocrine tumors

,

diabetes mellitus

,

type 1 diabetes mellitus

,

immunologic deficiency syndromes

,

intestinal neoplasms

,

endometrioid carcinoma

,

stem cell transplantation

,

biliary atresia

,

dilated cardiomyopathy

,

,

peripheral arterial disease

,

peripheral vascular diseases

,

ductal carcinoma

,

intraductal carcinoma noninfiltrating

,

respiratory aspiration

,

transitional cell carcinoma

,

chronic limb-threatening ischemia

,

,

neuroendocrine carcinoma

,

alveolar soft part sarcoma

,

adenosquamous carcinoma

,

choriocarcinoma

,

embryonal carcinoma

,

endodermal sinus tumor

,

,

inflammatory breast neoplasms

,

extranodal nk-t-cell lymphoma

,

t-cell lymphoma cutaneous

,

large-cell lymphoma immunoblastic

,

,

,

systemic lupus erythematosus

,

aids-related lymphoma

,

rheumatoid arthritis

,

lymphoproliferative disorders

,

precancerous conditions

,

erythroblastic leukemia acute

,

mucinous cystadenocarcinoma

,

serous cystadenocarcinoma

,

cystadenocarcinoma

,

merkel cell carcinoma

,

neurofibrosarcoma

,

,

paroxysmal hemoglobinuria

,

,

kidney transplantation

,

ischemic stroke

,

,

thrombocytopenia

,

,

bronchiolitis obliterans syndrome

,

severe acute respiratory syndrome

,

carcinoma in situ

,

ductal carcinoma breast

,

cystic fibrosis

,

nontuberculous mycobacterium infections

,

mycobacterium infections

,

pancreatic ductal carcinoma

,

gallbladder neoplasms

,

urologic neoplasms

,

,

adenocarcinoma of lung

,

bronchiolo-alveolar adenocarcinoma

,

large cell carcinoma

,

,

hypereosinophilic syndrome

,

bone marrow transplantation

,

homologous transplantation

,

non-gestational choriocarcinoma

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

sezary syndrome

,

immunoblastic lymphadenopathy

,

mycosis fungoides

,

adult t-cell leukemia-lymphoma

,

intraocular lymphoma

,

plasmablastic lymphoma

,

lymphomatoid granulomatosis

,

gastrointestinal neoplasms

,

islet cell carcinoma

,

small cell carcinoma

,

,

reactive arthritis

,

pathologic complete response

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

mast-cell leukemia

,

glandular and epithelial neoplasms

,

thymus neoplasms

,

biliary tract neoplasms

,

,

stiff-person syndrome

,

nerve sheath neoplasms

,

pure red-cell aplasia

,

leukoencephalopathies

,

progressive multifocal leukoencephalopathy

,

adenocarcinoma in situ

,

necrotizing enterocolitis

,

food intolerance

,

,

,

,

,

,

,

chagas cardiomyopathy

,

epidermolysis bullosa

,

epidermolysis bullosa dystrophica

,

,

cerebral infarction

,

,

dyskeratosis congenita

,

cognitive dysfunction

,

severe acute respiratory syndrome-related coronavirus

,

,

unilateral breast neoplasms

,

hypersensitivity

,

kidney diseases

,

immunosuppression therapy

,

,

trophoblastic neoplasms

,

,

,

,

invasive hydatidiform mole

,

,

megakaryoblastic leukemia acute

,

monocytic leukemia acute

,

bile duct neoplasms

,

laryngeal neoplasms

,

ulcerative colitis

,

,

,

,

,

,

,

congenital bone marrow failure syndromes

,

soft tissue neoplasms

,

disease progression

,

,

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

,

,

,

ovarian neoplasms

,

hodgkin disease

,

myeloproliferative disorders

,

b-cell chronic lymphocytic leukemia

,

,

b-cell lymphoma

,

,

non-small-cell lung carcinoma

,

ovarian epithelial carcinoma

,

neoplasm metastasis

,

large b-cell lymphoma diffuse

,

,

pancreatic neoplasms

,

central nervous system neoplasms

,

renal cell carcinoma

,

nervous system neoplasms

,

brain neoplasms

,

,

pulmonary alveolar proteinosis

,

kidney neoplasms

,

graft vs host disease

,

rhabdomyosarcoma

,

hematopoietic stem cell transplantation

,

triple negative breast neoplasms

,

primary myelofibrosis

,

medulloblastoma

,

small cell lung carcinoma

,

,

stomach neoplasms

,

,

,

,

,

communicable diseases

,

uveal neoplasms

,

myeloid leukemia chronic-phase

,

refractory anemia with excess of blasts

,

,

,

neuroectodermal tumors

,

respiratory distress syndrome

,

liver cirrhosis

,

autoimmune diseases

,

,

,

ganglioneuroblastoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

primitive neuroectodermal tumors

,

male breast neoplasms

,

,

head and neck neoplasms

,

refractory anemia

,

,

philadelphia chromosome

,

,

urinary bladder neoplasms

,

hematologic diseases

,

sickle cell anemia

,

cutaneous malignant melanoma

,

endometrial neoplasms

,

drug-related side effects and adverse reactions

,

residual neoplasm

,

immunoglobulin light-chain amyloidosis

,

classical conditioning

,

,

multiple sclerosis

,

,

systemic scleroderma

,

diffuse scleroderma

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

end stage liver disease

,

hemoglobinopathies

,

t-cell leukemia

,

,

induction chemotherapy

,

relapsing-remitting multiple sclerosis

,

critical illness

,

coronary artery disease

,

myocardial ischemia

,

phenylketonurias

,

acute-on-chronic liver failure

,

,

anterior wall myocardial infarction

,

radiation effects

,

,

,

coronavirus infections

,

,

alveolar rhabdomyosarcoma

,

embryonal rhabdomyosarcoma

,

coronary disease

,

inferior wall myocardial infarction

,

shwachman-diamond syndrome

,

,

,

,

,

cytomegalovirus retinitis

,

,

cutaneous leishmaniasis

,

,

,

giant cell tumors

,

pigmented villonodular synovitis

,

giant cell tumor of tendon sheath

,

localized scleroderma

,

neuromyelitis optica

,

,

diamond-blackfan anemia

,

adrenal cortex neoplasms

,

adrenocortical carcinoma

,

,

,

,

progression-free survival

,

,

choroid plexus neoplasms

,

left ventricular dysfunction

,

angina pectoris

,

,

sickle cell trait

,

invasive fungal infections

,

,

,

tongue neoplasms

,

,

,

myeloid leukemia acute

,

myeloid leukemia

,

,

multiple myeloma

,

myelodysplastic syndromes

,

plasma cell neoplasms

,

breast neoplasms

,

,

non-hodgkin lymphoma

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

prostatic neoplasms

,

,

lymphoid leukemia

,

hematologic neoplasms

,

,

chemotherapy-induced febrile neutropenia

,

myelomonocytic leukemia juvenile

,

,

myelomonocytic leukemia chronic

,

aplastic anemia

,

,

febrile neutropenia

,

,

,

,

myocardial infarction

,

,

,

,

,

alcoholic hepatitis

,

,

,

chronic hepatitis b

,

hepatic insufficiency

,

female infertility

,

chronic hepatitis

,

,

,

premature birth

,

primary ovarian insufficiency

,

premature menopause

,

,

,

wounds and injuries

,

hematopoietic stem cell mobilization

,

respiratory insufficiency

,

stevens-johnson syndrome

,

alcoholic liver diseases

,

female genital neoplasms

,

neonatal sepsis

,

spontaneous abortion

,

habitual abortion

,

arterial occlusive diseases

,

,

,

intermittent claudication

,

abnormal karyotype

,

lupus nephritis

,

,

hemophagocytic lymphohistiocytosis

,

retinal neoplasms

,

tissue adhesions

,

glycogen storage disease type ii

,

diabetic neuropathies

,

neurodegenerative diseases

,

chromosome aberrations

,

acute liver failure

,

,

,

brain hypoxia-ischemia

,

beta-thalassemia

,

hypoplastic anemia congenital

,

graft vs leukemia effect

,

,

breast carcinoma in situ

,

graft rejection

healthy volunteers/patients

,

bcr-abl positive chronic myelogenous leukemia

,

,

breast neoplasms

,

,

chronic renal insufficiency

,

,

kidney diseases

,

type 2 diabetes mellitus

,

diabetes mellitus

healthy volunteers/patients

,

colonic neoplasms

,

malignant mesothelioma

,

,

,

bronchiolitis obliterans syndrome

,

lymphoid leukemia

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

,

prostatic neoplasms

,

hypereosinophilic syndrome

,

,

systemic scleroderma

,

diffuse scleroderma

,

colorectal neoplasms

,

myeloid leukemia acute

,

,

non-small-cell lung carcinoma

,

ovarian neoplasms

,

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia juvenile

,

,

,

ovarian epithelial carcinoma

,

hematologic diseases

,

graft vs host disease

,

chronic disease

,

myeloid leukemia accelerated phase

,

localized scleroderma

,

systemic mastocytosis

,

primary myelofibrosis

,

myelomonocytic leukemia acute

,

,

renal cell carcinoma

,

thyroid neoplasms

,

thyroid diseases

,

head and neck neoplasms

,

squamous cell carcinoma

,

squamous cell neoplasms

,

,

,

,

,

urogenital neoplasms

,

male genital diseases

,

prostatic diseases

,

abdominal neoplasms

,

male genital neoplasms

,

genital diseases

,

,

,

,

neoplasm metastasis

,

non-hodgkin lymphoma

,

,

t-cell lymphoma

,

nephrogenic fibrosing dermopathy

,

b-cell chronic lymphocytic leukemia

,

myelodysplastic syndromes

,

,

hypersensitivity

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

desmoplastic small round cell tumor

,

,

myeloproliferative disorders

,

small cell lung carcinoma

,

dermatofibrosarcoma

,

autonomic nervous system diseases

,

,

rheumatoid arthritis

,

,

,

hematologic neoplasms

,

,

,

pulmonary arterial hypertension

,

familial primary pulmonary hypertension

,

,

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

gastrointestinal stromal tumors

,

philadelphia chromosome

,

myeloid leukemia chronic-phase

,

,

breast neoplasms

,

congenital abnormalities

,

chromosome aberrations

,

chromosome disorders

,

stomach neoplasms

,

polycythemia vera

,

myeloid leukemia acute

,

myeloid leukemia

,

healthy volunteers/patients

,

myelodysplastic syndromes

,

,

renal cell carcinoma

,

streptococcal infections

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

non-small-cell lung carcinoma

,

,

colorectal neoplasms

,

,

sjogren's syndrome

,

pancreatic ductal carcinoma

,

,

multiple myeloma

,

primary myelofibrosis

,

,

pancreatic neoplasms

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

,

triple negative breast neoplasms

,

ovarian neoplasms

,

plasma cell neoplasms

,

,

,

,

oligodendroglioma

,

,

chronic hepatitis c

,

chronic hepatitis

,

,

graft rejection

,

,

falciparum malaria

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

hematologic neoplasms

,

meningococcal infections

,

ovarian epithelial carcinoma

,

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

colonic neoplasms

,

neoplasm micrometastasis

,

uterine cervical neoplasms

,

rheumatoid arthritis

,

autoimmune diseases

,

systemic lupus erythematosus

,

breast neoplasms

,

,

,

,

chronic urticaria

,

,

,

haemophilus infections

,

liver transplantation

,

,

,

chronic renal insufficiency

,

kidney diseases

,

psoriatic arthritis

,

,

,

influenza in birds

,

chronic disease

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

gouty arthritis

,

,

,

autoimmune hepatitis

,

juvenile arthritis

,

,

haemophilus influenzae

,

hyperphosphatemia

,

chronic hepatitis b

,

,

cryopyrin-associated periodic syndromes

,

,

lupus nephritis

,

,

vascular diseases

,

polypoidal choroidal vasculopathy

,

h5n1 subtype influenza a virus

,

,

human influenza

,

kidney transplantation

,

,

,

,

,

,

tick-borne encephalitis

,

,

communicable diseases

,

cystic fibrosis

,

h1n1 subtype influenza a virus

,

cytomegalovirus infections

,

,

,

healthy volunteers/patients

,

follicular lymphoma

,

large b-cell lymphoma diffuse

,

non-hodgkin lymphoma

,

b-cell lymphoma

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

breast neoplasms

,

liver neoplasms

,

,

non-small-cell lung carcinoma

,

,

urologic neoplasms

,

urinary bladder neoplasms

,

transitional cell carcinoma

,

uterine cervical neoplasms

,

rheumatoid arthritis

,

,

kidney diseases

,

kidney transplantation

,

alzheimer disease

,

,

hepatocellular carcinoma

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

esophageal neoplasms

,

biliary tract neoplasms

,

,

,

,

hematologic neoplasms

,

multiple myeloma

,

plasma cell neoplasms

,

colorectal neoplasms

,

,

disability evaluation

,

cognition disorders

,

,

,

chronic hepatitis b

,

,

,

chronic hepatitis

,

,

multiple sclerosis

,

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